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Microsoft Adds Anthropic Models to 365 Copilot

by Team Lumida
September 25, 2025
in AI
Reading Time: 4 mins read
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Microsoft’s AI Ambitions: A Costly Path Forward

FILE PHOTO: A Microsoft logo is seen in Los Angeles, California, U.S. June 14, 2016. REUTERS/Lucy Nicholson

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Key Takeaways

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  • Microsoft will let business users of Microsoft 365 Copilot toggle between OpenAI and Anthropic models, adding Claude Opus 4.1 (for complex reasoning) and Claude Sonnet 4 (lighter) to Copilot’s Researcher feature and Copilot Studio.
  • The move diversifies Microsoft’s AI supply chain beyond OpenAI, giving customers model choice and reducing single‑vendor dependence.
  • Strategically, this strengthens Microsoft’s commercial Copilot offering and could accelerate enterprise adoption by matching models to task requirements.
  • Risks include extra integration and licensing costs, potential product complexity for customers, and the need to manage multiple model governance/safety standards alongside evolving terms with OpenAI.

What happened?

Microsoft announced that Anthropic’s Claude Opus 4.1 and Claude Sonnet 4 will be available as options inside Microsoft 365 Copilot features (Researcher and Copilot Studio), letting enterprise users switch between Anthropic and OpenAI models for research and agent‑creation tasks. The change reflects Microsoft’s strategy to aggregate best‑of‑industry models for workplace AI while it reworks its OpenAI relationship and scales its own in‑house models.

Why it matters

This integration meaningfully reduces Microsoft’s operational and reputational reliance on a single AI supplier and improves product flexibility for customers with different accuracy, safety and latency needs; that should make Copilot more attractive to large enterprises that value choice and risk management. For investors, the move supports Microsoft’s position as the primary commercializer of workplace AI, with potential upside to Azure consumption and Copilot subscription monetization if usage and retention rise. At the same time, supporting multiple third‑party models increases costs and complexity (integration, billing, safety compliance) and could create contractual or competitive tensions with OpenAI as Microsoft balances partnerships and its own model roadmap.

What’s next

Watch early usage and retention metrics for Copilot features that expose Anthropic models, and compare task performance and customer feedback versus OpenAI models to see which workloads migrate. Monitor Microsoft’s billing/pricing approach for multi‑model access, any formal commercial or exclusivity terms with Anthropic, and how Microsoft updates enterprise SLAs and safety controls to accommodate multiple providers. Also track whether this spurs broader multi‑model offerings from other cloud providers, and any shifts in Microsoft’s relationship with OpenAI or its investment in in‑house foundational models—those dynamics will determine revenue mix and gross‑margin implications over the next 6–12 months.

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Lumida's website (referred to herein as the "Website") is limited to the dissemination of general information pertaining to its advisory services, together with access to additional investment-related information, publications, and links. Accordingly, the publication of the Website on the Internet should not be construed by any client and/or prospective client Lumida’s solicitation to effect, or attempt to effect transactions in securities, or the rendering of personalized investment advice for compensation, over the Internet.

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